Bahcesehir University Molecular Biology and Genetics Department
Molecular Biology and Genetics Department within Faculty of Engineering and Natural Sciences at Bahcesehir University focuses on biosimilar production and anti-cancer drug development. Currently, there is one ongoing project on production of recombinant human Factor 8 in CHO cells for treatment of Hemophilia A. In the context of new drug development, cellular protein-protein interactions related with metastasis are being targeted by performing phage display and small molecule library screeing. Within the molecular biology lab, gene cloning, gene transfer into bacteria and mammalian cells, recombinant protein production, mRNA and protein expression analysis, mammalian cell culture studies, cytotoxicity assays, cell motility and invasion assays and phage display technology to identify cellular protein-protein interactions are being performed.